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KMID : 0371320000590050609
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Journal of the Korean Surgical Society
2000 Volume.59 No. 5 p.609 ~ p.620
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A Comparision of Cancer Related Survival Rate in Extreme Aged Gastric Cancer Patients
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Lee Jong-Hoon
Hyung Woo-Jin
Noh Sung-Hoon
Min Jin-Sik
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Abstract
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Purpose :Whether the clinical features of the gastric cancer in extremely aged patients differs from that in patients of ususal age has been controversial. The purpose of this study is to clarify the clinicopathologic features, including prognosis, especially cancer-related survival rates of gastric cancer in extremely age patients.
Methods :Among 3,104 gastric cancer patients who had received a gastrectomy from 1987 to 1995, a young age group (YOUNG), 153 patients under 5 percentile, aged ≤33, and an old age group (OLD), 139 patients over 95 percentile, aged ≥73, were compared retrospectively with usual age group (CONTROL); 609 patients of median 20 percentile, aged 53 to 58.
Results :YOUNG showed a female preponderance, a predominance of undifferentiated histology, and a higher peritoneal metastasis than CONTROL and OLD. OLD showed a lower prevalence of early gastric cancer and a preponderance of lower body location than YOUNG and CONTROL. The surgical extent of each group did not differ. YOUNG suffered less operative morbidity; however, the operative morbidity was similar between CONTROL and OLD. The operative mortality and the recurrence rate of the groups were not different. The prognosis of YOUNG was similar to that of
CONTROL. Because of the higher incidence of non-gastric cancer related deaths, the prognosis of OLD was poorer than that of CONTROL. However, the stomach cancer related survival rates of the groups were not different.
Conclusion :Although some clinicopathologic differences are seen between the age groups, they demonstrate similar cancer related survival rate as long as a gastrectomy is performed. Extreme age is neither a poor prognostic factor nor a factor for limiting of the extent of the gastrectomy. However, early diagnosis still remains the prerequisite for improving the prognosis for gastric cancer in extremely aged patients.
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KEYWORD
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Gastric cancer, Age, Clinicopathologic feature, Prognosis,
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